Step 1: Identify the relationship in BOOK:RIVER.
A book is a smaller entity compared to a river in its own category? Not literal. Think of analogy type: Both are channels — a book channels information, a river channels water.
More fitting is a book contains smaller parts, like a river contains streams/paths, but the given answer choices hint toward scale or type relation.
Step 2: Check options.
(A) Vein:artery — both are blood vessels but different roles; not matching book:river.
(B) Path:highway — both are routes for travel, differing in scale; analogous to the functional similarity/difference in scale of book:river (both channels).
(C) Yard:alley — no clear similar relationship.
(D) Pen:paper — tool and medium, not parallel.
\[
\boxed{\text{(B) Path : highway}}
\]