Question:

Select the correctly matched pair.

Updated On: Jul 27, 2022
  • Cosmid - Cannot be used in human genome project
  • BAC - 300-350 kb of foreign DNA
  • YAC - Can clone fragments upto 45kb in length only
  • Phagemid - An RNA based cloning vector carrying an origin of replication derived from adenovirus.
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The Correct Option is B

Solution and Explanation

Bacterial artificial chromosome (BAC) vectors are based on natural, extra-chromosomal plasmid of E.coii. These vectors can accommodate upto 300-350 kb of foreign DNA and are also being used in genome sequencing project.
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Concepts Used:

Biotechnology

Biotechnology is a vast field of biology that involves the creation, production, and modification of useful products for human welfare using both the technology and the execution of living organisms and their components. An agricultural engineer, Karoly Ereky, coined the word "biotechnology" in 1919, achieving him the title of "Father of Biotechnology."

Principles of Biotechnology:

Among many, the two core techniques that entitled the birth of modern biotechnology are :

  1. Genetic Engineering is one of the methods of direct modifications of an organism's genome (i.e., DNA and RNA). It requires the introduction of new genes into host species to escalate function or trait, hence altering the host organism's phenotype.
  2. Bioprocess Engineering is one of the methods of maintaining sterile conditions to facilitate the growth of large quantities of desired microbes and other eukaryotic cells for the development of new or modified biotechnological products such as enzymes, vaccines, antibiotics, and other biotechnological products.