Question

Resectability criteria for pancreatic cancer.

Hint:

Resectability of pancreatic cancer depends on the tumor's relationship with surrounding structures, particularly blood vessels and lymph nodes.

Answer 1

Resectability criteria for pancreatic cancer help in determining whether the tumor can be surgically removed. Pancreatic cancer is often diagnosed at advanced stages, and only a subset of patients are candidates for surgery. The resectability criteria include factors such as tumor size, location, and involvement of nearby blood vessels.
Step 1: Criteria for Resectability:
1. Localized Disease: The tumor should be confined to the pancreas and not involve distant organs or metastasize to other parts of the body.
2. Vascular Involvement: The tumor should not invade critical blood vessels such as the mesenteric artery, celiac axis, or superior mesenteric vein. Involvement of these vessels generally makes the tumor unresectable.
3. Lymph Node Involvement: Minimal or no lymph node involvement is preferred for resectability. If lymph nodes are involved, surgery may not be possible.
Step 2: Advanced Imaging Techniques:
1. CT Scan and MRI: These imaging techniques help in assessing the tumor’s size, location, and vascular involvement to determine whether it is resectable.
2. Endoscopic Ultrasound (EUS): EUS helps evaluate tumor proximity to major blood vessels, providing critical information for surgical planning.