Question

“Red man syndrome” has been associated with rapid intravenous injection of the following antibiotics:

• A. Clindamycin
• B. Vancomycin
• C. Piperacillin
• D. Linezolid

Hint:

To prevent Red man syndrome, Vancomycin should be infused slowly, and in some cases, antihistamines may be administered.

Answer 1

The Correct Option is B

Red man syndrome is a well
-known side effect associated with the rapid intravenous infusion of Vancomycin. This syndrome is characterized by flushing, rash, and sometimes hypotension, and it occurs due to the release of histamine from mast cells.
- Vancomycin is the antibiotic most commonly associated with this syndrome, especially when administered too quickly.
- Clindamycin, Piperacillin, and Linezolid are not commonly associated with Red man syndrome. Vancomycin
-induced Red man syndrome can often be mitigated by slowing the infusion rate or pre
-treating the patient with antihistamines. Thus, the correct answer is Vancomycin.