Question

Physiological dose of hydrocortisone (mg/kg/day) is

• A. 5 mg/kg/day
• B. 10 mg/kg/day
• C. 15 mg/kg/day
• D. 20 mg/kg/day

Answer 1

The Correct Option is B

In biochemistry and medicine, the physiological dose of a drug refers to the amount typically required to achieve normal bodily function in a healthy individual. For hydrocortisone, which is a corticosteroid hormone involved in the metabolism of carbohydrates, proteins, and fats as well as the management of stress responses and inflammation, the physiological dose is important for ensuring these normal body functions without causing side effects.

The generally accepted physiological dose of hydrocortisone is 10 mg/kg/day. This dose ensures adequate cortisol activity in the body, which is essential for maintaining various metabolic processes and aiding in stress response.

Options provided were:

• 5 mg/kg/day
• 10 mg/kg/day
• 15 mg/kg/day
• 20 mg/kg/day

Among these options, 10 mg/kg/day is the correct physiological dose of hydrocortisone.