Question:

Nucleosome is associated with ______ molecules of histones.

Updated On: Mar 26, 2025
  • Four
  • Nine
  • Two
  • Eight
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The Correct Option is D

Solution and Explanation

Nucleosome Structure 

The fundamental repeating unit of chromatin in eukaryotic cells is the nucleosome. Its basic function is to package and order the DNA into a compact structure.

Composition:

  • Each nucleosome consists of a complex of eight histone proteins. These eight proteins form the histone octamer.
  • DNA is wrapped around this histone octamer.

Details:

  • The eight histone proteins are:
    • Two H2A histones
    • Two H2B histones
    • Two H3 histones
    • Two H4 histones
  • Approximately 146 base pairs of DNA are wrapped around the histone octamer.

The linker DNA, which is approximately 20-80 base pairs in length, connects adjacent nucleosomes.

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