Question:

Nucleosome is:

Updated On: Mar 26, 2025
  • Positively charged DNA wrapped around negatively charged histone octamer
  • Negatively charged DNA wrapped around positively charged histone octamer
  • Positively charged DNA wrapped around positively charged histone octamer
  • Negatively charged DNA wrapped around negatively charged histone octamer
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The Correct Option is B

Approach Solution - 1

Nucleosomes are the fundamental units of chromatin, where negatively charged DNA is wrapped around a positively charged histone protein octamer. This structure helps in compacting DNA within the nucleus.
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Approach Solution -2

A nucleosome is the basic structural unit of chromatin, which is made up of DNA wrapped around histone proteins.

  • DNA is negatively charged due to the phosphate groups in its backbone.
  • Histone proteins are positively charged because they contain a high proportion of amino acids like lysine and arginine, which are positively charged.

The nucleosome is formed when the negatively charged DNA wraps around the positively charged histone octamer, which consists of eight histone proteins (H2A, H2B, H3, and H4 in pairs).

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