Question:

Neonate with GI bleeding: 
Etiology. 
 

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When assessing neonates with GI bleeding, it is important to consider both medical conditions (like NEC or coagulopathies) and procedural trauma as potential causes.
Updated On: Dec 10, 2025
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Solution and Explanation

Step 1: Understanding GI bleeding in neonates.
Gastrointestinal (GI) bleeding in neonates can be a life-threatening condition that requires prompt diagnosis and management. It can result from several underlying causes, ranging from benign conditions to more severe pathologies.

Step 2: Etiology of Neonatal GI Bleeding.
1. Gastric ulcers: Neonates, especially preterm infants, may develop stress ulcers in the stomach, often due to exposure to medications like corticosteroids or invasive procedures.
2. Infections: Infections such as necrotizing enterocolitis (NEC) or viral gastroenteritis can lead to bleeding in the intestinal tract.
3. Coagulopathies: Neonates, especially those with liver disease, vitamin K deficiency, or certain genetic disorders, may have abnormal blood clotting, leading to bleeding from the GI tract.
4. Anatomical anomalies: Conditions such as malrotation, intestinal atresia, or vascular malformations can cause GI bleeding in neonates. 5. Trauma: Birth trauma or invasive procedures like nasogastric tube insertion can cause mucosal damage and bleeding in the GI tract.

Step 3: Conclusion.
The most common causes of GI bleeding in neonates include infections like NEC, coagulopathies, anatomical abnormalities, and stress ulcers. Trauma due to medical procedures can also contribute to the bleeding.

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