Question:
Mechanism of action of propyl thiouracil ………
Mechanism of action of propyl thiouracil ………
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PTU blocks thyroid hormone synthesis via thyroid peroxidase inhibition.
Updated On: May 22, 2025
- Inhibition of thyroid peroxidase
- Activation of thyroid peroxidase
- Inhibition of thyroid oxidase
- Activation of thyroid oxidase
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The Correct Option is A
Solution and Explanation
Propylthiouracil (PTU) inhibits thyroid peroxidase, thereby blocking the iodination of tyrosine residues in thyroglobulin, an essential step in thyroid hormone synthesis. It also inhibits peripheral conversion of T4 to T3.
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