Question

Match the drug/chemicals listed in Column I with the developmental/physiological defects listed in Column II.

• A. P-(iii); Q-(iv); R-(ii); S-(i)
• B. P-(i); Q-(iv); R-(iii); S-(ii)
• C. P-(ii); Q-(iv); R-(iii); S-(i)
• D. P-(ii); Q-(iii); R-(iv); S-(i)

Hint:

Different drugs and chemicals can lead to specific congenital defects or physiological disorders. Always remember the major historical examples like Thalidomide for Phocomelia and Methylmercury for Minamata syndrome.

Answer 1

The Correct Option is A

Step 1: Understanding the drugs and defects.
- Veratrum alkaloids (P) are known to cause Cyclopia (iii), a birth defect where there is only one eye.
- Thalidomide (Q) is famous for causing Phocomelia (iv), which is a condition where limbs are severely shortened or absent.
- Methylmercury (R) is responsible for causing Minamata syndrome (ii), a neurological disease caused by mercury poisoning.
- Diethylstilbestrol (S) is linked with obesity (i) and other hormonal disruptions, particularly in offspring.
Step 2: Analyzing the options.
- (A) Correct, as it correctly matches each drug to its respective defect: Veratrum alkaloids with Cyclopia, Thalidomide with Phocomelia, Methylmercury with Minamata syndrome, and Diethylstilbestrol with Obesity.
- (B), (C), and (D) are incorrect because they do not match the defects correctly with the drugs.
Step 3: Conclusion.
Thus, the correct answer is (A) P-(iii); Q-(iv); R-(ii); S-(i).