Question

Match LIST-I with LIST-II

Choose the correct answer from the options given below:

• A. A - I, B - II, C - III, D - IV
• B. A - I, B - III, C - II, D - IV
• C. A - I, B - II, C - IV, D - III
• D. A - III, B - IV, C - I, D - II

Hint:

Associate keywords: Anthrax \(\rightarrow\) Wool sorters. Gas gangrene \(\rightarrow\) Clostridium. UTI \(\rightarrow\) E. coli. Cervical Cancer \(\rightarrow\) HPV. These are classic pairings in medical microbiology.

Answer 1

The Correct Option is D

Step 1: Understanding the Concept:
This question requires matching common infectious diseases with their specific causative agents (pathogens).
Step 2: Detailed Explanation:
Let's match each disease with its pathogen:


A. Wool sorter's disease: This is the historical name for inhalational anthrax, a severe lung infection caused by inhaling the spores of the bacterium Bacillus anthracis. The name comes from its association with workers who sorted wool from infected animals. This matches III.

B. Gas gangrene: This is a life-threatening infection of muscle tissue (myonecrosis) characterized by gas production. The primary causative agent is the anaerobic, spore-forming bacterium Clostridium perfringens. This matches IV.

C. Urinary tract infection (UTI): While many bacteria can cause UTIs, the vast majority (around 80-90\%) of community-acquired cases are caused by the bacterium Escherichia coli (E. coli). This matches I.

D. Cervical cancer: Most cases of cervical cancer are caused by persistent infection with certain high-risk strains of the Human papillomavirus (HPV). This virus integrates into the host genome and produces oncoproteins that lead to malignant transformation. This matches II.

Step 3: Final Answer:
The correct matching is A-III, B-IV, C-I, D-II.