Question:
Many people have consumed contaminated alcohol and present with abdominal pain, confusion, and decreased vision. Methyl alcohol concentration detected as 20 mg percent. On assessment, which metabolites will be found?
Many people have consumed contaminated alcohol and present with abdominal pain, confusion, and decreased vision. Methyl alcohol concentration detected as 20 mg percent. On assessment, which metabolites will be found?
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In methanol poisoning, glycolic acid and oxalic acid are important metabolites to identify, and their presence in blood can confirm the diagnosis.
Updated On: Mar 24, 2025
- Formic acid and lactic acid
- Glycolic acid and oxalic acid
- Oxalic acid and formic acid
- Glyoxylic acid and formic acid
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The Correct Option is B
Solution and Explanation
Methyl alcohol (methanol) is metabolized in the liver to formaldehyde and formic acid, which can cause metabolic acidosis. However, the ingestion of methanol also leads to the accumulation of glycolic acid and oxalic acid, which contribute to the toxic effects and metabolic acidosis.
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