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Management of intraoperative hypotension during craniotomy procedures.

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Effective management of intraoperative hypotension involves a combination of monitoring, fluid therapy, vasopressors, and appropriate adjustments to anesthetic agents to ensure adequate perfusion and prevent complications.
Updated On: Dec 11, 2025
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The management of intraoperative hypotension during craniotomy procedures involves prompt recognition and appropriate interventions to maintain adequate cerebral perfusion and prevent further complications. Treatment strategies include both pharmacological and non-pharmacological approaches.
Step 1: Monitoring and Assessment:
1. Continuous Blood Pressure Monitoring: Intraoperative blood pressure should be continuously monitored using an arterial line, especially in high-risk patients, to detect hypotension early.
2. Cerebral Perfusion Monitoring: Monitoring devices such as near-infrared spectroscopy (NIRS) can be used to assess cerebral oxygenation, helping guide treatment decisions.
3. Hemodynamic Parameters: It is essential to monitor cardiac output, heart rate, and central venous pressure to assess the cause of hypotension.
Step 2: Non-Pharmacological Management:
1. Positioning: The patient’s position should be optimized to enhance venous return, particularly during craniotomy. Positioning the head appropriately, avoiding excessive tilting, and ensuring proper neck alignment can help improve circulation.
2. Fluid Resuscitation: Intravenous fluids (e.g., crystalloids, colloids) should be administered to correct any volume deficits and restore blood pressure. A target mean arterial pressure (MAP) should be set based on the patient's condition and surgical requirements.
Step 3: Pharmacological Management:
1. Vasopressors: Drugs like phenylephrine, norepinephrine, or ephedrine can be used to increase systemic vascular resistance and raise blood pressure in the event of hypotension.
2. Inotropes: In cases where hypotension is due to reduced cardiac output, inotropes such as dobutamine may be used to enhance myocardial contractility.
3. Adjusting Anesthetic Agents: If hypotension is related to excessive vasodilation from anesthetics, adjustments should be made to the depth of anesthesia, or vasoconstrictors can be added to counteract the effects.
Step 4: Correction of Blood Loss:
1. Transfusion: If significant blood loss occurs during surgery, blood products (such as red blood cells, plasma, or platelets) should be administered to replace lost volume and improve oxygen-carrying capacity.
Step 5: Postoperative Care:
1. Continued Hemodynamic Monitoring: After the surgery, the patient should be monitored in the recovery room or intensive care unit for any signs of residual hypotension or complications.
2. Pain Control: Adequate pain control should be maintained to prevent hypotension associated with pain-induced sympathetic activation.
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