Question

Major substrates for gluconeogenesis are………

• A. Pyruvate
• B. Fructose
• C. Glucose
• D. Malate

Hint:

Pyruvate is the main precursor for gluconeogenesis—it's the entry point to synthesize glucose when carbohydrate levels are low.

Answer 1

The Correct Option is A

Gluconeogenesis is the metabolic process of generating glucose from non-carbohydrate sources. Pyruvate is a key starting substrate in this process. It is converted to oxaloacetate and then to phosphoenolpyruvate, eventually forming glucose. While other intermediates like malate may be involved, pyruvate is the principal substrate.