Step 1: Mad Cow disease is caused by prions, which are misfolded proteins that affect the nervous system of infected animals. It can spread to humans via consumption of beef products infected with prions.
Step 2: Creutzfeldt - Jacob disease is the human equivalent of Mad Cow disease and can be contracted by humans who consume infected beef. It is a prion disease that leads to severe neurological symptoms.
Step 3: Therefore, the correct answer is option (4) Creutzfeldt - Jacob disease.