Question:

Lithium causes:

Updated On: Jul 15, 2025
  • Hypokalemia
  • Hyperkalemia
  • Hypocalcemia
  • Hypercalcemia
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The Correct Option is A

Solution and Explanation

In understanding the effects of lithium on electrolyte balance, it's essential to examine lithium's role in the biochemistry of the body. Lithium is a mood stabilizer often used in the treatment of bipolar disorder. It is known to influence various ion channels and transporters in cells, particularly within the kidneys.
The question asks about which differential electrolyte imbalance is caused by lithium. The correct answer is hypokalemia.
Explanation:
Lithium can affect the sodium-potassium-ATPase pump in renal tubular cells, leading to increased renal excretion of potassium. This relationship impacts potassium levels in the blood, causing hypokalemia (low potassium levels). Potassium is vital for cellular function, nerve transmission, and muscle contraction, and its deficiency can lead to symptoms such as muscle weakness, cramping, and arrhythmias.
Conclusion: Lithium's impact on renal function and electrolyte balance makes hypokalemia a primary concern. Monitoring potassium levels is crucial in patients receiving lithium therapy to prevent this condition.
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