We simplify the inequality:
\[
\frac{x^{-1} - y^{-1}}{x^2 - y^2} = \frac{\frac{y - x}{xy}}{(x - y)(x + y)} = \frac{y - x}{xy(x - y)(x + y)}.
\]
Since \( y - x = -(x - y) \), this becomes:
\[
\frac{-1}{xy(x + y)}.
\]
Thus, the expression is negative for positive \( x \) and \( y \). Therefore, it can never be \( > 1 \) if both \( x \) and \( y \) are positive integers greater than 2.
From Statement I: \( x + y > 0 \) is not enough because \( x \) and \( y \) could be negative or positive, so the sign and magnitude of the expression are uncertain. Hence, insufficient.
From Statement II: \( x, y \) are positive integers \( > 2 \), which makes the denominator positive and large, while the numerator is \(-1\), so the fraction is negative, meaning the inequality \( > 1 \) is false. Hence, sufficient to answer without I.