Question:

Increased Km and unchanged Vmax is seen in which of the following inhibition? 

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In competitive inhibition, the inhibitor competes with the substrate, which increases the Km (affinity decreases), but Vmax remains unchanged.
Updated On: Mar 24, 2025
  • Competitive inhibition
  • Noncompetitive inhibition
  • Uncompetitive inhibition
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The Correct Option is A

Solution and Explanation

In competitive inhibition, the inhibitor competes with the substrate for the active site of the enzyme, leading to an increase in the apparent Km (lower affinity) but no change in Vmax (the maximum reaction rate).
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