Question

In type 2 diabetes mellitus, pancreatic beta cells initially respond to insulin resistance by………

• A. Enhancing glucose uptake by peripheral tissues
• B. Decreasing insulin secretion
• C. Suppressing glucagon secretion
• D. Increasing insulin secretion

Hint:

Early response to insulin resistance = Increased insulin secretion by beta cells.

Answer 1

The Correct Option is D

In the early stages of type 2 diabetes, pancreatic beta cells try to compensate for insulin resistance by increasing insulin secretion. This hyperinsulinemia helps maintain normoglycemia initially, but over time, beta-cell function declines.