Question

In tRNA, the region that binds with mRNA is:

• A. Anticodon loop of tRNA
• B. Amino acid acceptor end of tRNA
• C. Amino acyl synthetase loop of tRNA
• D. Ribosomal binding loop of tRNA

Hint:

The anticodon-codon interaction ensures the fidelity of protein translation.

Answer 1

The Correct Option is A

In tRNA structure and function:

(A) Anticodon loop of tRNA - Correct: This region contains the anticodon that base-pairs with the mRNA codon during translation.

(B) Amino acid acceptor end tRNA - Incorrect: This 3' end binds the amino acid, not mRNA.

(C) Amino acyl synthetase loop of tRNA - Incorrect: This interacts with aminoacyl-tRNA synthetase enzymes.

(D) Ribosomal binding loop of tRNA - Incorrect: This helps position tRNA in the ribosome but doesn't bind mRNA.

The correct answer is (A) Anticodon loop of tRNA, as this is the specific region that recognizes and binds complementary mRNA codons.

Answer 2

tRNA (transfer RNA) plays a crucial role in protein synthesis by carrying specific amino acids to the ribosome and pairing them with the corresponding codons on mRNA. The key regions of tRNA include:

• Anticodon loop : Contains the anticodon, which is complementary to the codon on mRNA. This is the region that binds to mRNA during translation.
• Amino acid acceptor stem : Attaches to the specific amino acid.
• Ribosomal binding site : Interacts with the ribosome.

The region responsible for binding to mRNA is the anticodon loop , as it contains the anticodon that base-pairs with the codon on mRNA.