Question:

In recent years,DNA sequences (nucleotide sequence) of mt-DNA and Y chromosomes were considered for the study of human evolution,because:

Updated On: Apr 3, 2024
  • They are small,and therefore,easy to study
  • They are uniparental in origin and do not take part in recombination
  • Their structure is known in greater detail
  • They can be studied from the samples of fossil remains
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The Correct Option is B

Solution and Explanation

Mitochondrial DNA (mt-DNA) and the Y chromosome are inherited in a uniparental manner. Mitochondrial DNA is inherited exclusively from the mother, and the Y chromosome is inherited exclusively from the father. They do not undergo genetic recombination, unlike nuclear DNA. This lack of recombination makes them valuable for tracking specific genetic lineages and ancestry over time, making them useful tools in the study of human evolution.

So, the correct option is (B): They are uniparental in origin and do not take part in recombination

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Concepts Used:

Human Genome Project

The Human Genome Project was an international research effort designed to map out the DNA sequence of an entire human genome. It was the first undertaking of its kind and took over a decade to complete. The goal of the Human Genome project was to sequence and identify the entire Human genome. And then store the entire genome information in a database. The Human Genome Project required improvement tools for data analysis.

The Human Genome Project (HGP) was an international, collaborative research program whose goal was the complete mapping and understanding of all the genes of human beings. All our genes together are known as our "genome."

Goals of the Human Genome Project

The HGP set out to establish the following goals: 

  1. First, to identify all the approximately 20,000-25,000 genes that make up the human DNA.
  2. Map out the genome sequences of the 3 billion chemical base pairs that comprise the human DNA.
  3. Ensure the storage of the derived information in genome sequence databases.
  4. Optimize the tools required for the data analysis process.
  5. Handle the ethical, legal, and social issues (ELSI) that may arise during the project.

The shotgun phase of the Human Genome Project itself consisted of three steps:

  1. Obtaining a DNA clone to sequence
  2. Sequencing the DNA clone
  3. Assembling sequence data from multiple clones to determine overlap and establish a contiguous sequence

Impact of Human Genome Research

The Human Genome Project will entirely reshape the approach to all biomedical research as well as therapeutic and preventive health care. The development in fields like bioinformatics and biostatistics will allow for better pattern detection and analysis of genetic disorders. 

Students interested in a deeper analysis of the Human Genome Project can visit the official website created by the National Institute of Health.