Comprehension
In normal cells, progress through the cell cycle is tightly regulated and each step must be completed before the next step can begin. There are at least three distinct points in the cell cycle at which the cell monitors external signals and internal equilibrium before proceeding to the next stage. These are the G1/S, the G2/M and M checkpoints.
In addition to regulating the cell cycle at the checkpoints, the cell controls progress through the cell cycle by means of two classes of proteins: cyclins and cyclin-dependent kinases (CKDs).
Based on the above context, answer the following questions :
In addition to regulating the cell cycle at the checkpoints, the cell controls progress through the cell cycle by means of two classes of proteins: cyclins and cyclin-dependent kinases (CKDs).
Based on the above context, answer the following questions :
Question: 1
Event that occurs at G1/S checkpoint is :
Event that occurs at G1/S checkpoint is :
Updated On: Mar 15, 2024
- Cell monitors DNA synthesis and damage
- Cell monitors spindle formation
- Attachment to kinetochores
- Cell monitors size and DNA integrity
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The Correct Option is D
Solution and Explanation
The correct answer is (D) : Cell monitors size and DNA integrity.
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Question: 2
Given below are two statements:
Statement I: Continuously dividing cells do not exit the cell cycle but they proceed through G1, S, G2 and M phase.
Statement II: Cancer cells are unable to enter GO phase.
In the light of the above statements, choose the correct answer from the options given below :
Given below are two statements:
Statement I: Continuously dividing cells do not exit the cell cycle but they proceed through G1, S, G2 and M phase.
Statement II: Cancer cells are unable to enter GO phase.
In the light of the above statements, choose the correct answer from the options given below :
Statement I: Continuously dividing cells do not exit the cell cycle but they proceed through G1, S, G2 and M phase.
Statement II: Cancer cells are unable to enter GO phase.
In the light of the above statements, choose the correct answer from the options given below :
Updated On: Mar 15, 2024
- Both Statement I and Statement II are correct
- Both Statement I and Statement II are incorrect
- Statement I is correct but Statement II is incorrect
- Statement I is incorrect but Statement II is correct
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The Correct Option is A
Solution and Explanation
The correct answer is (A) : Both Statement I and Statement II are correct.
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Question: 3
Choose the correct statement :
Choose the correct statement :
Updated On: Mar 15, 2024
- Cyclin D2 accumulates during early G1 phase
- Cyclin E appears during S phase
- Cyclin B peaks during M phase
- Cyclin A appears during late G1 phase
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The Correct Option is D
Solution and Explanation
The correct answer is (D) : Cyclin A appears during late G1 phase.
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