Question

In germ line gene therapy, healthy gene is inserted into:

• A. Hepatic cells
• B. Embryonic cells
• C. Erythroblast
• D. Sperm or Eggs

Hint:

Somatic gene therapy targets non-reproductive cells and the changes are not inherited.Germline therapy is complex and raises many ethical considerations because it has im- plications for future generations.

Answer 1

The Correct Option is D

Germline gene therapy involves inserting a functional gene into germ cells (sperms or eggs) or very early-stage embryos. This ensures that the genetic modification is heritable, meaning the change will be passed down to future generations. This method aims to correct genetic defects not just in an individual but also in their future progeny. Options A, B and C (Hepatic, fibroblast and endothelium cells) are somatic cells, which are not passed down to future generations.