Question:
Imipenem,a newer antibiotic with a broad antibacterial spectrum, is co administered with cilastatin. Which of the following is the best reason for the same?
Imipenem,a newer antibiotic with a broad antibacterial spectrum, is co administered with cilastatin. Which of the following is the best reason for the same?
Updated On: Aug 21, 2024
- Combination of antibiotics is synergistic against Pseudomonas specie
- Cilastatin aids gastrointestinal absorption of active moiety, imipenem
- Cilastatin inhibits beta=lactamase enzyme destroying imipenem
- Cilastatin inhibits an enzyme in kidney destroying imipenem
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The Correct Option is D
Solution and Explanation
The correct option is (D) : Cilastatin inhibits an enzyme in kidney destroying imipenem
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