Step 1: Differentiate the given equation.
Differentiate \( (x + y) \sin u = x^2 y^2 \) with respect to \( x \) and \( y \) using implicit differentiation. Then solve for \( x \frac{\partial u}{\partial x} + y \frac{\partial u}{\partial y} \).
Step 2: Conclusion.
Thus, the correct answer is option (D).
Final Answer:
\[
\boxed{\text{(D) } \tan u}
\]