Let $ A = \begin{bmatrix} 2 & 2 + p & 2 + p + q \\4 & 6 + 2p & 8 + 3p + 2q \\6 & 12 + 3p & 20 + 6p + 3q \end{bmatrix} $ If $ \text{det}(\text{adj}(\text{adj}(3A))) = 2^m \cdot 3^n, \, m, n \in \mathbb{N}, $ then $ m + n $ is equal to:
Draw a rough sketch for the curve $y = 2 + |x + 1|$. Using integration, find the area of the region bounded by the curve $y = 2 + |x + 1|$, $x = -4$, $x = 3$, and $y = 0$.
Study the given molecular structure of double-stranded polynucleotide chain of DNA and answer the questions that follow. 
(a) How many phosphodiester bonds are present in the given double-stranded polynucleotide chain?
(b) How many base pairs are there in each helical turn of double helix structure of DNA? Also write the distance between a base pair in a helix.
(c) In addition to H-bonds, what confers additional stability to the helical structure of DNA?
