Question:

Identify the microorganism which is responsible for the production of an immunosuppressive molecule cyclosporin A:

Updated On: May 2, 2025
  • Trichoderma polysporum
  • Clostridium butylicum
  • Aspergillus niger
  • Streptococcus cerevisiae
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The Correct Option is A

Solution and Explanation

The production of the immunosuppressive molecule cyclosporin A is attributed to a specific microorganism. This task falls within the scientific field of microbiology, which studies various microorganisms, their behaviors, and beneficial uses.

To identify the microorganism responsible, we focus on the properties of cyclosporin A. It is a cyclic peptide used widely in transplantation medicine to prevent rejection, functioning by suppressing the immune system. Research and historical data point to a particular fungus known for producing this compound.

Let's review the options given:

  • Trichoderma polysporum
  • Clostridium butylicum
  • Aspergillus niger
  • Streptococcus cerevisiae

From the options listed, Trichoderma polysporum is acknowledged as the source microorganism for cyclosporin A. The reasoning is based on extensive scientific documentation highlighting Trichoderma species' abilities to produce bioactive compounds, including protective metabolites like cyclosporin A. The other listed microorganisms are known for different biological activities:

  • Clostridium butylicum is primarily known for producing butyric acid.
  • Aspergillus niger is typically associated with citric acid production.
  • Streptococcus cerevisiae is incorrectly named; likely referring to Saccharomyces cerevisiae, which is a yeast used in baking and brewing.

Therefore, the microorganism responsible for producing cyclosporin A is correctly identified as Trichoderma polysporum.

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Concepts Used:

HIV and AIDS

What Is HIV?

HIV is a virus that attacks cells that help the body to fight infection and  making a person more vulnerable to other infections and diseases. It is spread by contact with certain bodily fluids of a person with HIV. It is most commonly during the unprotected sex or when share injection or drugs equipment.

What Is AIDS?

It is the late stage of HIV infection that occurs when the body’s immune system is badly damaged because of the virus.