The incorrect statement is (4) Angina pectoris is a warning signal.
Explanation:
Angina pectoris is actually a classic symptom of coronary artery disease (CAD). It's characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle. This reduced blood flow is often due to the buildup of plaque in the coronary arteries, which is the hallmark of CAD.
Therefore, angina pectoris serves as an important warning sign that there's an underlying issue with the coronary arteries. It's not incorrect to associate angina with CAD; rather, it's a crucial indicator of the disease.
The other statements are correct:
Accumulation of calcium, fat, cholesterol in coronary artery: This is the primary cause of CAD, leading to plaque buildup and narrowing of the arteries.
Death of myocardial cells: While cell death can occur in severe cases of CAD (like during a heart attack), it's not the defining characteristic of the disease itself.
Associated with smoking: Smoking is a major risk factor for CAD.