Step 1: Understanding the genetic cross.
In the case of human skin color, a cross between pure black and pure white parents would follow Mendelian inheritance patterns. The F2 generation from this cross will show a variety of genetic combinations. Multihybrid individuals would be those showing multiple traits (multihybrid).
Step 2: Analyzing the options.
(A) One: Incorrect — The F2 generation will have more than one multihybrid.
(B) Six: Incorrect — Six multihybrid individuals is not the expected outcome.
(C) Twenty: Correct — In the F2 generation of a dihybrid cross, about 20% will be multihybrids.
(D) Fifteen: Incorrect — Fifteen multihybrids are not the expected number for this genetic cross.
Step 3: Conclusion.
The correct answer is (C) Twenty, as the expected number of multihybrids is twenty among the 64 offspring.