Question

How is a polypeptide bond formed?

Hint:

Polypeptide bonds are key in the formation of proteins, linking amino acids through dehydration reactions.

Answer 1

Step 1: Polypeptide Bond Formation.
A polypeptide bond is formed during protein synthesis when the carboxyl group (\( \text{COOH} \)) of one amino acid reacts with the amino group (\( \text{NH}_2 \)) of another amino acid. This reaction leads to the elimination of a water molecule (dehydration) and the formation of a covalent bond called a peptide bond.
Step 2: Example.
For example, when glycine (\( \text{NH}_2\text{CH}_2\text{COOH} \)) reacts with alanine (\( \text{NH}_2\text{CH}_3\text{COOH} \)), a peptide bond is formed, resulting in the dipeptide glycine-alanine and the release of water.