HCV (Hepatitis C virus) syndrome refers to a range of systemic manifestations that occur due to chronic infection with the hepatitis C virus. These may include liver-related complications and extrahepatic manifestations.
Step 1: Extrahepatic Manifestations:
1. Cryoglobulinemia: A condition where abnormal proteins in the blood cause inflammation, leading to vasculitis.
2. Rashes and Arthralgia: Common in HCV infection, often linked to immune complex deposition.
3. Kidney Disease: Glomerulonephritis, particularly membranoproliferative glomerulonephritis, is a common manifestation.
Step 2: Hepatic Manifestations:
1. Chronic Hepatitis: Long-term liver inflammation, which can progress to cirrhosis or liver cancer.
2. Liver Failure: In advanced stages, chronic HCV infection can lead to liver failure.