Question:

Grape fruit juice is P- glycoprotein and CYP40 enzyme inhibitor. if drug X is degraded by proteolytic enzymes, administration of grapefruit juice with X

Updated On: Jul 16, 2024

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The Correct Option is B

The correct option is (B) : Decrease Bioavailability of X

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	List I		List II
A	When two dosage forms have equal t max	I	When their total body clearance is constant.
B	AUC values of the two analogs can be compared to measure relative bioavailability	II	Absorption rate constants are equal
C	Urinary data is valid to measure bioavailability. III. W	III	When fraction absorbed and elimination rate is constant.
D	C max is proportional to the rate of absorption	IV	Excretion of drug and/or metabolite is related to the bioavailable dose.

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Antibody	Description
P. IgE	(i) Cross the placenta
Q. IgG	(ii) Dominant antibody produced in immune responses
R. IgM	(iii) It is found in the mother's milk
S. IgA	(iv) Responsible for autoimmune responses including allergies

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