Frequency of recombination between gene pairs on same chromosome as a measure of the distance between genes to map their position on chromosome, was used for the first time by
Frequency of recombination between gene pairs on same chromosome as a measure of the distance between genes to map their position on chromosome, was used for the first time by
Sutton and Boveri
Alfred Sturtevant
Henking
Thomas Hunt Morgan
The Correct Option is B
Approach Solution - 1
The concept of measuring the frequency of recombination between gene pairs on the same chromosome to map their position on a chromosome was first utilized by Alfred Sturtevant. As a student of Thomas Hunt Morgan, Sturtevant recognized that the likelihood of recombination between two gene loci is proportional to the distance separating them. This insight allowed him to create the first genetic map, using recombination frequency as a measure of distance—a pivotal advancement in the field of genetics.
Thus, the correct answer is: Alfred Sturtevant.
Approach Solution -2
Alfred Sturtevant was the first to propose and use the frequency of recombination between gene pairs on the same chromosome as a measure of the distance between genes. This concept laid the foundation for genetic mapping, and his work was performed in collaboration with Thomas Hunt Morgan's laboratory.
Therefore, The correct option is (B): Alfred Sturtevant
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Concepts Used:
Recombinant Technology
Recombinant DNA technology is the process used for producing new genetic combinations by joining different genetic material (DNA) together and inserting them into host organisms from two different species or sources. These new combinations are of value to medicine, science, industry, and agriculture.
Process of Recombinant DNA Technology:
Step 1- Isolation of Genetic Material.
Step 2- Cutting the gene at the recognition sites.
Step 3- Amplifying the gene copies through Polymerase chain reaction ( PCR)
Step 4- Ligation of DNA Molecules.
Step 5- Insertion of Recombinant DNA into Host.
Application of Recombinant DNA Technology:
- In agricultural fields Recombinant DNA Technology plays a major role. It produces genetically-modified organisms such as flavor save tomatoes, golden rice rich in protein and lot more
- Recombinant DNA technology is also used to produce Insulin.
- ELISA is one kind of clinical diagnosis where recombinant DNA technology is used.
- Recombinant DNA technology prevents hereditary diseases through gene therapy and also detects the presence of HIV in a person.