Let's analyze the pattern in the sequence:
- The numbers alternate between 53 and 40 and 27.
- The pattern of numbers is:
53, 53, 40, 40, 27, 27.
Each number repeats twice, and the sequence decreases by 13 each time:
- From 53 to 40, the difference is -1(3)
- From 40 to 27, the difference is -1(3)
Following this pattern, the next number after 27 will also be 14, as we are again decreasing by 1(3)
Thus, the missing number is \( \boxed{14} \).
Therefore, the correct answer is \( \boxed{2} \).