Question

Explain the causes of Klinefelter's syndrome. Also mention the symptoms of this syndrome.

Hint:

Klinefelter's syndrome is one of the most common chromosomal disorders but often goes undiagnosed due to mild symptoms.

Answer 1

Step 1: Causes of Klinefelter's Syndrome. - Klinefelter's syndrome is caused by a genetic anomaly where a male is born with an extra X chromosome, resulting in a 47,XXY karyotype instead of the typical 46,XY. - This syndrome occurs due to non-disjunction during meiosis in one of the parents, leading to an extra X chromosome in the sperm or egg.
Step 2: Symptoms of Klinefelter's Syndrome. - Males with Klinefelter's syndrome often have reduced testosterone levels, leading to delayed puberty, infertility, and gynecomastia (development of breast tissue). - They may also experience learning difficulties, particularly with language and motor skills.
Final Answer: Klinefelter's syndrome occurs due to the presence of an extra X chromosome (47,XXY), and its symptoms include infertility, delayed puberty, gynecomastia, and learning difficulties.