Solution:
The disappearance of the nucleolus and the nuclear envelope occurs during prophase of karyokinesis.
Explanation:
In prophase, the early phase of mitosis or meiosis, several key events take place:
These processes are crucial for the subsequent steps of karyokinesis, where the chromosomes will be moved and separated into daughter cells. The nuclear envelope and nucleolus reassemble later in telophase when the division is nearing completion.