Question:

During DNA replication, the strands separate by

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During DNA replication, the DNA opens up, and strands separate to allow transcription or replication of DNA.

Updated On: Aug 20, 2024
  • DNA polymerase
  • topoisomerase
  • unwindase/helicase
  • gyrase

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The Correct Option is C

Solution and Explanation

During DNA replication, the DNA opens up, and strands separate by unwindase/helicase. This is done to allow for transcription as well as replication of our DNA.

  • The molecule is unwound by DNA unwinding proteins known as helicases. 
  • A DNA helicase or 'Unwindase' is an enzyme that melts the hydrogen bonds to hold the DNA in the double helix structure.  
  • The helicases II and III get attached to the logging strand and protein is attached to the leading strand. 
  • The formation of bands is avoided by SSB or single stranded DNA binding proteins.

So, the correct option is 'unwindase/Helicase'.

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Concepts Used:

The Molecular Basis of Inheritance

DNA Replication:

DNA synthesis is commenced at particular points within the DNA strand referred to as ‘origins’, which are certain coding regions. There are numerous origin sites, and when replication of DNA starts, these sites are mentioned as replication forks. Within the replication, the complex is the enzyme DNA Helicase, so that they can be utilized as a template for replication. DNA Primase is another enzyme that's essential in DNA replication.

RNA:

Ribonucleic acid (RNA) is an essential biological macromolecule that exists all together in biological cells. It is principally involved in the synthesis of proteins, that carry the messenger instructions from DNA, which itself contains the genetic instructions needed for the event and maintenance of life. In some viruses, RNA, in spite of DNA, carries genetic information.

Genetic Code:

Genetic code is the term we use in the manner that the four bases of DNA--the A, C, G, and Ts--are strung together in a way that the ribosome, the cellular machinery, can read them and switch them into a protein. In the ordering, every three nucleotides during a row count as a triplet and code for one amino alkanoic acid.

Read More: Molecular Basis of Inheritance