Question

Describe histological structure of Testis with well labelled diagram.

Hint:

Think of the testis as a factory. The seminiferous tubules are the "assembly lines" where sperm are made, Sertoli cells are the "workers" providing support, and Leydig cells in the "office" (interstitial space) produce the hormone (testosterone) that runs the factory.

Answer 1

The testis is the primary male reproductive organ, responsible for producing sperm and male hormones. Its histological structure is highly organized for these functions. Histological Structure:

Coverings: The testis is enclosed by three layers. The outermost is the Tunica vaginalis (a peritoneal covering), followed by a dense, fibrous capsule called the Tunica albuginea. The innermost layer is the Tunica vasculosa, which is rich in blood vessels. 
Testicular Lobules: The Tunica albuginea extends inwards to form septa that divide the testis into about 250 conical compartments called testicular lobules. 
Seminiferous Tubules: Each lobule contains one to three highly coiled tubes known as seminiferous tubules. These are the functional units of the testes where spermatogenesis (sperm production) occurs. 
Germinal Epithelium: The wall of each seminiferous tubule is lined by a complex stratified epithelium called the germinal epithelium. This epithelium consists of two main types of cells: 

Spermatogenic Cells: These are the male germ cells at various stages of development, from the outermost spermatogonia to primary spermatocytes, secondary spermatocytes, spermatids, and finally spermatozoa (sperm) near the lumen. 
Sertoli Cells (Sustentacular Cells): These are large, supportive cells that extend from the basement membrane to the lumen of the tubule. They nourish and support the developing sperm cells, form the blood-testis barrier, and secrete hormones like inhibin. 

Interstitial Space: The space between the seminiferous tubules is called the interstitial space. It is filled with connective tissue, blood vessels, and specialized endocrine cells. 
Leydig Cells (Interstitial Cells): Located in the interstitial space, these cells are responsible for synthesizing and secreting male sex hormones (androgens), primarily testosterone, which is crucial for spermatogenesis and the development of male secondary sexual characteristics. 
Diagram (T.S. of Testis):