Question:

Define Minimal Alveolar Concentration (MAC) of inhaled anaesthetic agents.

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MAC is a useful concept to assess the potency of inhaled anaesthetics. The lower the MAC, the more potent the anaesthetic agent.
Updated On: Dec 10, 2025
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Solution and Explanation

Step 1: Definition of MAC.
Minimal Alveolar Concentration (MAC) is the concentration of an inhaled anaesthetic agent in the alveoli that prevents movement in 50% of patients exposed to a standard surgical stimulus. It is used as a measure of the potency of inhaled anaesthetics. A lower MAC value indicates a more potent anaesthetic agent, as it requires a lower concentration to achieve the desired effect of preventing movement during surgery.

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