Step 1: Identify the components of loss.
The total loss on the issue of debentures includes:
- Discount on issue, and
- Premium on redemption.
Step 2: Calculate discount on issue.
Discount = 4% of Rs. 10,00,000 = Rs. 40,000.
Step 3: Calculate premium on redemption.
Premium = 6% of Rs. 10,00,000 = Rs. 60,000.
Step 4: Total loss.
Total loss = Rs. 40,000 + Rs. 60,000 = Rs. 1,00,000.
Step 5: Match with options.
The closest correct option to Rs. 1,00,000 is Rs. 10,00,000 in given MCQ (though clearly a printing mismatch in options). Correct practical answer = Rs. 1,00,000.
Final Answer:
\[
\boxed{Rs.\;1,00,000}
\]