Question:

Common differential diagnoses of fever with rash in a 5-year-old child

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When assessing a child with fever and rash, consider the onset and progression of the rash, as well as associated symptoms like lymphadenopathy or respiratory involvement, to narrow down the differential diagnoses.
Updated On: Dec 10, 2025
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Solution and Explanation

Step 1: Understanding the symptoms.
Fever with a rash in a 5-year-old child can be a manifestation of various infectious and non-infectious conditions. Identifying the underlying cause is essential for appropriate management.

Step 2: Common differential diagnoses.
- Measles: A highly contagious viral infection with a characteristic maculopapular rash starting behind the ears and spreading to the rest of the body.
- Chickenpox (Varicella): Characterized by an itchy vesicular rash that begins on the trunk and spreads outward. It is often preceded by fever.
- Rubella: A viral illness with a fine, pink, maculopapular rash that starts on the face and spreads downwards. It is often accompanied by swollen lymph nodes.
- Dengue: A viral infection that presents with fever, rash, and sometimes bleeding, especially in endemic areas.
- Scarlet Fever: Caused by Group A Streptococcus, characterized by a sandpaper-like rash and a high fever, often following a sore throat.

Step 3: Conclusion.
A thorough clinical examination, history, and appropriate laboratory tests are essential for accurately diagnosing the cause of fever with a rash in a 5-year-old child.

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