Chronic auto immune disorder affecting neuro muscular junction leading to fatigue, weakening and paralysis of skeletal muscle is called as :
Gout
Arthritis
Muscular dystrophy
Myasthenia gravis
The Correct Option is D
Solution and Explanation
To solve this question, we need to identify which condition is a chronic autoimmune disorder affecting the neuromuscular junction, leading to fatigue and weakness of skeletal muscles.
Let's analyze each option:
- Gout: Gout is a type of arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. It is caused by excess uric acid in the blood. It is not an autoimmune disorder affecting neuromuscular junctions.
- Arthritis: Arthritis is a general term for conditions that affect the joints and tissues around the joint. It can be caused by multiple factors, including wear and tear, infections, and autoimmune reactions. However, it does not typically focus on the neuromuscular junction and skeletal muscle fatigue.
- Muscular dystrophy: Muscular dystrophy refers to a group of genetic disorders characterized by muscle degeneration and weakness. While it affects the muscles, it is primarily a genetic disorder and not an autoimmune disorder affecting the neuromuscular junction.
- Myasthenia gravis: Myasthenia gravis is indeed a chronic autoimmune disorder that affects the neuromuscular junction. It causes weakness and rapid fatigue of voluntary (skeletal) muscles. This condition fits the description given in the question.
Therefore, the correct answer is Myasthenia gravis. This condition specifically targets the communication between nerves and muscles, leading to muscle fatigue and weakness as described.
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Concepts Used:
Immune System
It consists of tissues, cells, soluble molecules like antibodies and lymphoid organs. The WBC cells called the leucocytes have a significant role as they seek out to destroy the disease-causing organisms. These leucocytes are stored in different locations in the body including the spleen, bone marrow, and thymus. These organs are called as the lymphoid organs. The leucocytes are also present in the lymph nodes of the body.It is considered as the main lymphoid orga and. It produces all the blood cells including the lymphocytes. The thymus is an organ that is present near to the heart, beneath the breastbone.
