The correct transformation of an affirmative sentence into an interrogative sentence in simple present tense (with "she") uses "Does."
"Does she teach Mathematics?" is grammatically correct. Why other options are incorrect:
- "Do she" is incorrect because "Do" is not used with "she."
- "Is she a Mathematics teacher?" changes the structure and meaning.
- "Is Mathematics taught by her?" is passive voice and not the direct interrogative form.