Question:
Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (Use the internet).
Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (Use the internet).
Updated On: Oct 5, 2023
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Solution and Explanation
Recombinnant proteins are obtained from the recombinant DNA technology. This technology involves the transfer of specific genes from an organism into another organism using vectors and restriction enzymes as molecular tools.
Ten recombinant proteins used in medical practice are-
| S.No. | Recombinant protein | Therapeutic use |
| 1 | Insulin | Treatment for type I diabetes mellitus |
| 2 | Interferon-α | Used for chronic hepatitis C |
| 3 | Interferon - AZA2 | Used for herpes and viral enteritis |
| 4 | Coagulation factor VII | Treatment of hemophilia A |
| 5 | Coagulation factor IX | Treatment of hemophilia B |
| 6 | DNAse I | Treatment of cystic fibrosis |
| 7 | Anti-thrombin III | Prevention of blood clot |
| 8 | Interferon B | For the treatment of multiple sclerosis |
| 9 | Human recombinant growth hormone | For providing growth in an individual |
| 10 | Tissue plasminogen activator | Treatment of acute myocardial infection |
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Concepts Used:
Recombinant Technology
Recombinant DNA technology is the process used for producing new genetic combinations by joining different genetic material (DNA) together and inserting them into host organisms from two different species or sources. These new combinations are of value to medicine, science, industry, and agriculture.
Process of Recombinant DNA Technology:
Step 1- Isolation of Genetic Material.
Step 2- Cutting the gene at the recognition sites.
Step 3- Amplifying the gene copies through Polymerase chain reaction ( PCR)
Step 4- Ligation of DNA Molecules.
Step 5- Insertion of Recombinant DNA into Host.
Application of Recombinant DNA Technology:
- In agricultural fields Recombinant DNA Technology plays a major role. It produces genetically-modified organisms such as flavor save tomatoes, golden rice rich in protein and lot more
- Recombinant DNA technology is also used to produce Insulin.
- ELISA is one kind of clinical diagnosis where recombinant DNA technology is used.
- Recombinant DNA technology prevents hereditary diseases through gene therapy and also detects the presence of HIV in a person.