Nucleophilicity is the ability of a species to donate a lone pair to form a new bond. Factors like charge, electronegativity, and solvent affect nucleophilicity.
• Charge: Anionic species (OH-, NH2-) are stronger nucleophiles than neutral species (H2O, NH3), because of the high electron density resulting from the negative charge.
• Electronegativity: Within the same period, less electronegative atoms are better nucleophiles, for example N is less electronegative than O. NH2- is therefore a better nucleophile than OH-.
Therefore, the order of decreasing nucleophilicity is NH2- >OH->NH3>H2O