After maturation, in primary lymphoid organs, the lymphocytes migrate for interaction with antigens to secondary lymphoid organ(s)/tissue(s) like:
A. thymus
B. bone marrow
C. spleen
D. lymph nodes
E. Peyer's patches
Primary lymphoid organs (bone marrow and thymus) are where lymphocytes mature. Secondary lymphoid organs (spleen, lymph nodes, Peyer's patches, tonsils, and mucosa-associated lymphoid tissue (MALT)) are where mature lymphocytes encounter antigens and initiate immune responses. The thymus and bone marrow are sites of lymphocyte development, not the primary location for antigen interaction.