Question

After 4 months of renal transplantation, a patient can likely to develop which infection

• A. EBV
• B. CMV
• C. Candida
• D. Histoplasma

Answer 1

The Correct Option is B

Determining the infection a patient is likely to develop after 4 months post-renal transplantation involves understanding the different types of infections related to organ transplants. The immune system of transplant recipients is often suppressed due to medications, making them susceptible to various infections.

Within the first few months post-transplant, the most common infections are related to opportunistic viruses like Cytomegalovirus (CMV). CMV is a herpesvirus that can cause significant morbidity in immunocompromised patients, including those who have undergone organ transplantation. Its reactivation or primary infection usually occurs 1 to 6 months post-transplant.

Here is a breakdown of the options:

• EBV (Epstein-Barr Virus): Typically associated with post-transplant lymphoproliferative disorder (PTLD), which can occur later in the post-transplant period.
• CMV (Cytomegalovirus): Commonly reactivates during the second month to the six months post-transplant due to immunosuppression.
• Candida: Fungal infections like Candida are more common in the early post-operative period, especially within the first month, due to surgical sites and lines.
• Histoplasma: Fungal infections like Histoplasma are less common and depend on geographical exposure to the fungus.

Given the timeline of four months post-transplant, CMV is the most likely infection to develop.