Question

Acute fatty liver commonly seen in pregnancy at

• A. 3rd trimester
• B. 1st trimester
• C. Immediate postpartum
• D. Intrapartum

Answer 1

The Correct Option is A

Acute Fatty Liver of Pregnancy (AFLP) is a rare, serious condition that occurs during pregnancy. It is characterized by an excess accumulation of fat in liver cells, leading to liver dysfunction. This condition is potentially life-threatening for both mother and baby.

Conditions: AFLP typically presents later in pregnancy, often during the third trimester. The symptoms can include nausea, vomiting, abdominal pain, malaise, jaundice, and, in severe cases, it may progress to liver failure.

Pathophysiology: The exact cause is unclear, but it's thought to involve a deficiency in mitochondrial fatty acid oxidation due to a genetic issue in the degradation of fatty acids.

Diagnosis: Diagnosing AFLP involves a combination of clinical signs, laboratory tests showing abnormal liver function, and imaging studies, which exclude other liver diseases.

Treatment: The primary treatment for AFLP is the prompt delivery of the baby, which usually results in the resolution of the condition. Supportive care for the mother involves managing complications like coagulopathy and hypoglycemia.

Conclusion: Given these facts, the correct answer to the question of when acute fatty liver is commonly seen in pregnancy is 3rd trimester.