Question

According to NCEP-ATP III, which among the following have not been included in metabolic syndrome ?

• A. High LDL
• B. Hypertriglyceridemia
• C. Central Obesity
• D. Hypertension

Answer 1

The Correct Option is A

According to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), metabolic syndrome is characterized by a cluster of certain risk factors that increase the chance of developing cardiovascular diseases and diabetes. To diagnose metabolic syndrome, the presence of three or more of the following criteria is typically required:

• Waist Circumference indicating central obesity: A waist measurement of >102 cm (>40 inches) in men and >88 cm (>35 inches) in women.
• Hypertriglyceridemia: Triglyceride levels ≥150 mg/dL (1.7 mmol/L) or on treatment for elevated triglycerides.
• Low HDL Cholesterol: HDL cholesterol <40 mg/dL (1.03 mmol/L) in men and <50 mg/dL (1.29 mmol/L) in women, or on treatment for low HDL.
• Hypertension: Blood pressure ≥130/85 mmHg or on antihypertensive treatment.
• Impaired Fasting Glucose: Fasting plasma glucose level ≥100 mg/dL (5.6 mmol/L) or on treatment for elevated glucose.

Based on these criteria, high LDL cholesterol is not included as a component of the metabolic syndrome. High LDL levels are a risk factor for cardiovascular disease but are not specifically targeted in the definition of the metabolic syndrome according to NCEP-ATP III.