Question

A woman with recurrent diarrhea is prescribed a broad-spectrum antibiotic. Which of the following is not true regarding Clostridium difficile infection?

• A. Oral fidaxomicin is used for treatment
• B. It is toxin mediated
• C. IgM assay is used to confirm the diagnosis
• D. Pseudomembrane is a layer of inflammatory

Answer 1

The Correct Option is C

To address the question regarding Clostridium difficile infection, let's evaluate each statement:

• Oral fidaxomicin is used for treatment: This is a true statement. Fidaxomicin is a recommended antibiotic for treating C. difficile infections.
• It is toxin mediated: True. C. difficile infections are caused by toxins produced by the bacteria.
• IgM assay is used to confirm the diagnosis: This statement is false. Diagnosis of C. difficile infection is typically confirmed using stool tests for toxins or by polymerase chain reaction (PCR), not IgM assays.
• Pseudomembrane is a layer of inflammatory: True. A pseudomembrane forms in the colon during severe C. difficile infection, characterized by an inflammatory reaction.

Thus, the statement 'IgM assay is used to confirm the diagnosis' is not true regarding Clostridium difficile infection.